PTPRJ (protein tyrosine phosphatase, receptor type, J)

Expression and Function of the Protein Tyrosine Phosphatase Receptor J (PTPRJ) in Normal Mammary Epithelial Cells and Breast Tumors

The protein tyrosine phosphatase receptor J, PTPRJ, is a tumor suppressor gene that has been implicated in a range of cancers, including breast cancer, yet little is known about its role in normal breast physiology or in mammary gland tumorigenesis. In this paper we show that PTPRJ mRNA is expressed in normal breast tissue and reduced in corresponding tumors. Meta-analysis revealed that the gen...

PTPRA ( protein tyrosine phosphatase , receptor type , A )

Review on PTPRA, with data on DNA/RNA expression, on the protein encoded, and the functional importance of the gene.

UCSD MOLECULE PAGES Tyrosine-protein phosphatase non-receptor type 2

TC-PTP is a ubiquitous non-receptor type protein tyrosine phosphatase that shows highest expression in hematopoietic tissues. It regulates many signal transduction pathways in hematopoietic as well as non-hematopoietic cells. TCPTP has two splice variants, an endoplasmic reticulum-localized TC48, and predominantly nuclear TC45. Upon various stress conditions and insulin stimuli, TC45 comes out ...

PTPN 1 ( protein tyrosine phosphatase , non - receptor type 1 )

Protein Tyrosine Phosphatase Receptor Type g Is a JAK Phosphatase and Negatively Regulates Leukocyte Integrin Activation